Priligy (dapoxetine) is a medicine used to treat premature ejaculation in men. Premature ejaculation is a sexual dysfunction in which a male ejaculates earlier (typically in the first minute ) than desired during sexual intercourse.
Priligy prescribed for premature ejaculation treatment in men aged 18 to 64 years with the following:
Dapoxetine is a medication that belongs to the class of SSRIs. It increases serotonin levels in the brain which is the neurotransmitter that controls ejaculation. Although the exact process of the drug in the patient's body is not well understood, the results of clinical studies indicate the efficacy of dapoxetine in the treatment of premature ejaculation by influencing serotonin levels in the brain. Sexual intercourse duration or intravaginal ejaculatory latency time can be delayed by up to 30%.
According to numerous clinical studies from the University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training & Research Hospital, Department of Urology, dapoxetine is used to treat premature ejaculation. Study included 422 men with premature ejaculation who received dapoxetine or placebo. Men who received dapoxetine had better control over ejaculation and sexual satisfaction than the placebo group.
Priligy should be taken by mouth with or without food 1 to 3 hours before sexual intercourse. Recommended dose is 30 mg to 60 mg, but dose can be adjusted by the doctor depending on the patient's response. Duration of sexual intercourse can be increased by 30% using Priligy.
If you are experiencing any side effects that are bothering or alarming you from Priligy, you should consult your doctor. Dapoxetine therapy may be discontinued and other methods of premature ejaculation treatment may be considered.
Alcohol consumption should be avoided by patients taking dapoxetine because this practice may result in dizziness and drowsiness side effects. Dapoxetine and Priligy should not be combined with alcohol because this practice enhances neurocognitive effects of alcohol and neurocardiogenic adverse events including syncope which raises accidental injury risks thus patients should abstain from alcohol consumption during treatment.
Priligy cannot be prescribed to patients who receive monoamine oxidase inhibitors (MAOIs) or have discontinued MAOI therapy for the past 14 days. Patients should avoid thioridazine therapy as well as staying off thioridazine treatment for 14 days.
Patients cannot use Priligy with L-tryptophan or triptans or tramadol or linezolid or lithium or St. John's wort (Hypericum perforatum) or serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors (SNRIs) or tricyclic antidepressants (TCAs) or other serotonergic medicinal/herbal products.
Using Priligy with potent CYP3A4 inhibitors is strictly prohibited. Patients who take moderate CYP3A4 inhibitors should only receive a limited dose of 30 mg when these medications are used together. Drug class includes CYP3A4 inhibitors which are metabolized through the enzyme CYP3A4 together with other SSR inhibitors and SSNIs and antifungal drugs and drugs used to treat bacterial infections and HIV/AIDS drugs and other medications. Your doctor will give you a complete list of dapoxetine incompatibilities. Before starting any new medication you must disclose all your current medications including prescription drugs and over-the-counter products and herbal supplements.
Priligy is incompatible with drugs that are degraded by CYP3A4 enzyme, for instance, ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir, atazanavir, etc.
Dapoxetine is not suitable for patients who have bipolar disorder and severe clinical depression and seizure or syncope history along with kidney or liver or heart diseases and stomach or duodenum ulcer. You must consult with your doctor before starting premature ejaculation treatment to verify dapoxetine matches your requirements.
History of allergic reactions to the drug along with kidney or liver disease and heart disease and epilepsy and bipolar disorder and mania and depression and stomach ulcer and other diseases as identified by your healthcare provider represents dapoxetine contraindications.
Patients who have Priligy contraindications may find other premature ejaculation treatments useful including behavioral therapy and pelvic floor muscle strengthening exercises and alternative SSRI antidepressants to dapoxetine.
Priligy treatment will be prohibited by doctors for patients who experience syncope (fainting) or seizures. Dapoxetine must be prohibited to all patients who have experienced mania or severe depression.
Dapoxetine AlternativesSunrise Remedies Pvt. Ltd produces Super P-Force as a combination medication that unites sildenafil citrate 100mg with dapoxetine hydrochloride 60mg in one tablet. Pricing ranges from $2.50-4.50 per pill
Single tablet formulation of Super Kamagra by Ajanta Pharma Limited contains sildenafil citrate 100mg and dapoxetine hydrochloride 60mg to treat erectile dysfunction and premature ejaculation. Prices ranges from $2.80-4.80 per tablet.
Sunrise Remedies Pvt. Ltd. produces Tadapox, which combines tadalafil 20mg with dapoxetine 60mg in a single tablet to treat erectile dysfunction and premature ejaculation. Prices ranges from $3.50-5.80 per tablet.
On-demand premature ejaculation treatment medication Super Fildena from Fortune Healthcare which operates under Centurion Laboratories contains sildenafil citrate 100mg and dapoxetine hcl 60mg as dual-action combination medication. Ranges from $2.40-4.20 per tablet.
Sunrise Remedies Pvt. Ltd produces Super Avana which contains avanafil 200mg and dapoxetine 60mg. The FDA approved avanafil as a second-generation PDE5 inhibitor in 2012 which starts working within 15-30 minutes. Ranges from $4.50-7.00 per tablet.
Sunrise Remedies Pvt. Ltd produces Extra Super Avana which combines avanafil 200mg with dapoxetine 60mg and tadalafil 40mg into a single tablet. The triple-action medication exists in a price range of $3.80-6.50 per pill.
Extra Super P-Force contains sildenafil citrate 100mg, tadalafil 40mg, and dapoxetine 60mg. The product manufactured by Sunrise Pharmaceuticals exists in a price range of $3.00-6.50 per tablet.